Factory supply dmsa dimercaptosuccinic acid / dimercaptosuccinic acid succimer with CAS 304-55-2
  • Item No.TOP
    MOQ100 Gram / Grams
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    DMSA Powder is the organosulfur compound with the formula HO2CCH(SH)CH(SH)CO2H. This colorless solid contains two carboxylic acid and two thiol groups, the latter being responsible for its mildly unpleasant odour. It occurs in two diastereomers, meso and the chiral dl forms. The meso isomer is used as achelating agent. The acid is most often used as a treatment for heavy metal toxicity, and is a water soluble and non-toxic substance.

     

     

     

    COA

    ItemDMSA
    AppearanceWhite powder
    CAS304-55-2
    EINECS206-155-2
    MFC4H6O4S2
    Molecular weight182.218
    Density1.617 g/cm3
    Melting point196-198℃
    Boiling point267.57℃ at 760 mmHg
    Flash point115.622℃
    Storage-20℃
    Vapour pressure0.002mmHg at 25℃

     

    function

     

    DMSA Powder is indicated for the treatment of lead poisoning in children with blood level measured above 45 µg/dL. The use of DMSA is not approved for prophylactic/prevention of lead poisoning in anticipation of exposure in known lead contaminated environments. Its elimination half-life is 2.5-3.5 h. DMSA can cross the blood–brain barrier of mice, but not that of humans, limiting its use to extracting heavy metals from parts of the body other than the central nervous system.

     

    Another application for DMSA is for provocation of tissue heavy metals in anticipation of a urine test. This is sometimes called a "challenge" or "provoked" heavy metals test. DMSA is used to help mobilize heavy metals stored in body tissues (and therefore not typically present in the circulation) and increase the excretion of heavy metals in the urine. In a study by Howard Frumkin et al., this sort of test was shown to not reliably provide an indication of past chronic mercury exposure, something it was often used for. A 2004 study by GP Archbold, et al. called the results of a DMSA challenge test "misleading" for the purposes of diagnosing mercury toxicity. Moreover, DMSA share the limitation of extracellular distribution, which makes it unable to cross the cell membrane and chelate heavy metals from intracellular sites.

     

    The relative activities of a series of novel monoalkyl esters of meso-2,3-dimercaptosuccinic acid (DMSA) have been examined as agents for the mobilization of cadmium, lead and arsenic owing to the ability of these monoesters to cross cell membranes. The monoesters were found to be more effective than the parent compound DMSA. 

     

    Company Information

    Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
     
    The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.

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    FAQ
    Q1: Are you a manufacturer?
    Answer: Yes, we are factory founded on 2002.
     
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    Surely,It depend on your qty
     
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    free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
     
    Q6: How to confirm the Product Quality before placing orders?
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    Q7:How do you treat quality complaint?
    A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
     

     

     

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