Product Description
Fosfomycin tromethamine is a phosphonic acid bactericidal agent with in vitro activity against most urinary tract pathogens. It is particularly active against Escherichia coli, and Citrobacter, Enterobacter, Klebsiella, Serratia and Enterococcus spp. There appears to be little cross-resistance between fosfomycin and other antibacterial agents, possibly because it differs from other agents in its general chemical structure and site of action
Items | Specifications | Results |
Characteristics | White or almost white powder | Almost white powder |
Identification | IR: Complies | Complies |
Specific Rotation(anhydrous substance ) | -12.5°~-13.5° | -13.12° |
Water | ≤0.5% | 0.15% |
Acidity(pH ) | 3.5~5.5 | 4.88 |
Heavy Metals | ≤0.0010% | <0.0010% |
Phosphates | ≤0.0500% | <0.0500% |
Related Substances | Impurity A: ≤0.3% | Not detected |
Impurity B: ≤0.3% | 0.09% |
Impurity C: ≤0.1% | Not detected |
Impurity D: ≤0.1% | Not detected |
Unspecified impurity:≤0.1% | Not detected |
Total: ≤0.5% | 0.09% |
Residual Solvents | Methanol:≤0.3% | 0.10% |
Methyl tert-butyl ether: ≤0.5% | 0.00% |
Assay | 98.0%~102.0% | 100.50% |
Fosfomycin tromethamine is a bactericidal phosphonic acid derivative which acts primarily by inhibiting bacterial cell wall (peptidoglycan) synthesis. It has antibacterial activity against many pathogenic and opportunistic Gram-positive and Gram-negative bacteria isolated from patients with lower urinary tract infections (UTI). According to conventional in vitro susceptibility tests, fosfomycin has good activity against Escherichia coli, Staphylococcus aureus, and Serratia, Klebsiella, Citrobacter, Enterococcus and Enterobacter spp. Minimum inhibitory concentrations active against 90% of isolates (MIC90 values) for some other important pathogens are relatively high, but are well within the urinary concentrations of fosfomycin achieved during treatment with the drug.
Company Information
Qingdao Xigema Chemical Co., Ltd is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Xigema is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
Xigema has become the "Top 500 Chinese manufacturing companies","Top 20 of global chemical sales".Xigema has 21 subsidiaries and holding companies.
FAQ
Q1: Are you a manufacturer?
Answer: Yes, we are factory founded on 2002.
Q2: How to contact with us?
Click the Alibaba "Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
Q4:Can you give me a discount price?
Surely,It depend on your qty
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.