High quality 5-fluorouracile 5 fluorouracile with best price
  • Item No.TOP
    MOQ1 Kilogram / Kilograms
    description
    Product Description

    V2-Product Profile

    Product Name:  5-Fluorouracile

    EINECS No.: 200-085-6

    Type: Antineoplastic Agents

    CAS NO.: 51-21-8

    Molecular formula: C4H3FN2O2

    Molecular weight:130.08

    Appearance:white crystalline powder.

     

    V2-Test Report

    Items

    Specifications

    Results

    Appearance

    White to off-white crystalline powder

    Conform

    Identification

    A.                            IR

    Conform

    B.                           UV

    Conform

    C.                         HPLC

    Conform

    Loss on drying

    ≤0.5%

    0.06%

    Residue on ignition

    ≤0.1%

    0.03%

    Heavy metals

    ≤20ppm

    Conform

    Impurities F and Urea

    (TLC method)

    Impurity F≤0.25%

    Conform

    Urea≤0.20%

    Conform

    Related substance

    (HPLC method)

    Impurity A≤0.25%

    <0.01% (LOD)

    Impurity B≤0.25%

    <0.01% (LOD)

    Uracil≤0.15%

    <0.01% (LOD)

    5-Methoxyuracil≤0.15%

    0.08%

    Impurity E≤0.25%

    <0.01% (LOD)

    Any individual unspecified impurity

    ≤0.10%

    Each<0.05%

    (disregard limit)

    Total≤0.5%

    0.08%

    Assay (HPLC method)

    98.0-102.0%

    99.6%

    Bacterial endotomin

    ≤0.25 EU/mg

    Conform

    Mould and yeast count

    ≤100 cfu/g

    Conform

    Aerobic microbial count

    ≤1000 cfu/g

    Conform

    Escherichia coli

    Absent/g

    Absent/g

    Pseudomonas aeruginosa

    Absent/g

    Absent/g

    Staphylococcus aureus

    Absent/g

    Absent/g

    Conclusion

    The product meets the requirements of USP 37

    V2-Function

    Clinic for colon cancer, rectal cancer, gastric cancer, breast cancer, ovarian cancer,choriocarcinoma, malignant mole, head and neck squamous cell carcinoma, skin cancer, liver cancer, bladder cancer, etc.

     

    5-Fluorouracile is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. It is metabolized to ribonucleotides and deoxyribonucleotides, which can be incorporated into RNA and DNA. Treatment of cells with 5-FU leads to an accumulation of cells in S-phase and has been shown to induce p53 dependent apoptosis.

    V2-Applicaton

    1. It is used for biochemical studies and antitumor drugs.

    2. It is the anti tumor drug, also used for synthesis of flucytosine. 5- fluorouracil can be used in the study of rice in the

    biochemical studies, ear differentiation, genetic metabolic measurement, plant growth development research.

    3. It is used for the digestive system cancer, head and neck cancer, gynecological cancer, lung cancer, liver cancer,

    treatment of bladder cancer and skin cancer.

    4. Antimetabolite antitumor drugs.

    Packaging & Shipping

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    Company Information

    Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

    The aim of Qingdao Sigma Chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced
    processing technology and it has gained a high and reliable reputation from customers at both quality and services.

     

    Qingdao Sigma Chemical Co., Ltd has become the "Top 500 Chinese manufacturing companies",

    "Top 20 of global chemical sales".Qingdao Sigma Chemical Co., Ltdhas 21 subsidiaries and holding companies.

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    Team

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    Our Services

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    FAQ

    Q1: Are you a manufacturer?
    Answer: Yes, we are factory founded on 2002.
     
    Q2: How to contact with us?
    Click the Alibaba "Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
     
    Q3:Which kind of payment terms do you accept?
    For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
     
    Q4:Can you give me a discount price?
    Surely,It depend on your qty
     
    Q5:How can i get a sample?
    free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
     
    Q6: How to confirm the Product Quality before placing orders?
    A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
     
    Q7:How do you treat quality complaint?
    A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

    contact Us

    Have more questions about this product?

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    https://www.sigmachemical.com.cn/

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