Manufacturer pharma grade 99% Cabazitaxel with best price 183133-96-2
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    CabazitaxelCAS 183133-96-2Color:White
    MW: 835.93MSDS: Avaiable
    MF :C45H57NO14Sample: Avaiable
    Category: Oncology drugMin order: 1grams
    Quality standard Enterprise standard Place of Origin:China
    AppearanceWhite   powder
    Introductionis a semi-synthetic derivative of a natural taxoid.It was developed by Sanofi-Aventis and was approved by the U.S. Food and Drug  for the treatment of hormone-refractory prostate cancer on June 17, 2010. It is a microtubule inhibitor, and the fourth taxane to be approved as a cancer therapy.
    ApplicationsPharmaceutical raw materials , Oncology drug

     

    Test Report

    TEST ITEM

    SPECIFICATION

    Appearance

    White or almost white crystalline powder

    Identification

    FT-IR

    HPLC

    Water

    3.0%

    Melting Point

    148°C­—158°C 

    Residue on Ignition

    ≤0.1%

    Heavy metals

    ≤ 20ppm

     

     

     

     Residual  Solvents

    Acetone

    ≤ 5000ppm

    Dichloromethane

    ≤ 600ppm

    n-Hexane

    ≤ 290ppm

    Acetic acid

    ≤ 5000ppm

    Ethyl acetate

    ≤ 5000ppm

    Tetrahydrofuran

    ≤ 720ppm

    Ethanol

    ≤ 5000ppm

    Related

    substances

    cabazitaxel

    ≤ 0.3%

    10-DABIII

    ≤ 0.3%

    Any other single impurity

    ≤ 0.1%

    Total impurities

    ≤ 1.0%

    Chromatographic purity(By HPLC)

    ≥99.0%

     

    Function

    Cabazitaxel (previously XRP-6258) is a semi-synthetic derivative of a natural taxoid. It was developed by Sanofi-Aventis and was approved by the U.S for the treatment of hormone-refractory prostate cancer on June 17, 2010. It is a microtubule inhibitor, and the fourth taxane to be approved as a cancer therapy.

    Cabazitaxel in combination with prednisone is a treatment option for hormone-refractory prostate cancer following docetaxel-based treatment.

     

     Cabazitaxel anticancer mechanism and characteristics similar with docetaxel, belongs to anti-microtubule drugs. Cabazitaxel through binding to tubulin, promoting their assembly into microtubules, and can prevent these have assembled a microtubule disintegration of the stabilization of microtubules, thereby inhibiting cell mitosis, and interphase cellular functions (interphasecellularfunctions) of play.

      

    Packaging & Shipping

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    Our Services

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    FAQ
    Q1: Are you a manufacturer?
    Answer: Yes, we are factory founded on 2002.
     
    Q2: How to contact with us?
    Click the Alibaba "Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
     
    Q3:Which kind of payment terms do you accept?
    For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
     
    Q4:Can you give me a discount price?
    Surely,It depend on your qty
     
    Q5:How can i get a sample?
    free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
     
    Q6: How to confirm the Product Quality before placing orders?
    A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
     
    Q7:How do you treat quality complaint?
    A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
     
    Company Information

    Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

    The aim of Qingdao Sigma Chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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