High quality Ribonuclease A with best price 9001-99-4
  • Item No.TOP
    MOQ1 Gram / Grams
    description
    Product Description

    Product Description

     
    Pancreatic Ribonuclease (RNase I) catalyzes cleavage of the phosphodiester bond between the 5'-ribose of a nucleotide and the phosphate group attached to the 3'-ribose of an adjacent pyrimidine nucleotide forming a 2',3'-cyclic phosphate which may then be hydrolyzed to the corresponding 3'-nucleoside phosphate. Ribonuclease A has a molecular weight of 13,700 daltons. It operates in an optimum pH range of 7.0-7.5.

      

    Certification of Analysis

     

    Item

    Specification 

    Specific rotation

    +39.5 to +41.5° 

    State of solution(transmittance)

    Clear 99.0% min.

    Chloride[cl]

    0.020% max. 

    Ammonium [NH4]

    0.02% max. 

    Sulfate[SO4]

    0.020% max

    Iron[Fe]

    10ppm max.

    Heavy metals [Pb]

    10ppm max

    Arsenic[As2O3]

    1ppm max

    Other amino acids

    Chromatographically not detectable

    Loss on drying

    0.20% max. 

    Residue on ignition[sulfated]

    0.10% max.

    Assay

    99.0% min

     

     

    Function

     

    Used as a pharmaceutical intermediates.

     

    For biochemical research, determination of nucleic acid structure, medicine for the treatment of trauma and joint pain, inhibition of influenza and herpes virus, and for acute pancreatitis, epidemic encephalitis.

    For biochemical research, the determination of nucleic acid structure.

    Ribonuclease is an antiinflammatory enzyme preparation. It can catalyze the degradation of ribonucleic acid, can change the host cell metabolism. Inhibit viral synthesis. In vitro can inhibit the proliferation of influenza virus. In chicken embryo bone can inhibit vaccinia, herpes virus formation, and apply to acute pancreatitis. Its medicinal ointment is used locally for the treatment of trauma and joint pain.

    Daily intramuscular injection of 180mg, treatment of epidemic encephalitis.

    Sealed dry 0 ~ 40C preservation.

     

    Packaging & Shipping

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    Our Services

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