Hot sale high quality Quinine HCL 130-89-2
  • Item No.Quinine HCL
    MOQ1 Kilogram / Kilograms
    description
    Product Description

     Introduction of Quinine HCL

     

    Quinine HCL is a substance that was first obtained by processing the bark of the cinchona tree, a South American native plant that has been used as a fever reducer by Native Americans for centuries. This substance has been used historically to treat malaria, along with some other medical conditions, and although a number of antimalarial drugs are on the market today, it is still used in some regions. It is also used commercially as an additive to tonic water, a soft drink that is used as a mixer for other drinks in addition to being consumed straight.

     

    Nature Quinine is a natural white crystalline alkaloid having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), anti-inflammatory properties and a bitter taste. It is a stereoisomer of quinidine which, unlike Nature Quinine, is an anti-arrhythmic. Sulphate Quinine contains two major fused-ring systems: the aromatic quinoline and the bicyclic quinuclidine.

     

    Though it has been synthesized in the lab, the bark of the cinchona tree is the only known natural source of Nature Quinine. The medicinal properties of the cinchona tree were originally discovered by the Quechua Indians of Peru and Bolivia; later, the Jesuits were the first to bring the cinchona to Europe.

     Specification of Quinine HCL

     

    Items

    Specifications

    Appearance

    White or almost white or colourless, fine, silky needles, often in clusters

    Solubility

    Soluble in water, freely soluble in ethanol (96%).

    Identification

     

    A) TLC

    The principal spot in the chromatogram obtained with the test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with the reference solution.

    B) Bromine and ammonia

    A green colour develops when treated with bromine water and dilute ammonia

    C) Fluorescence

    When examined in ultraviolet light at 366 nm,an intense blue fluorescence appears which disappears almost completely on the addition of 1 ml of HCL

    D) Characteristic of chlorides

    It gives the reactions of chlorides

    E) Test for pH

    Should comply

    Appearance of solution

    Solution S is clear and not more intensely coloured than reference solution GY6

    pH

    6.0~6.8

    Specific optical rotation

    -245° ~  -258°

    Other cinchona alkaloids

    Impurity C

    Any impurity eluted before quinine

    Any other impurity

     

    NMT 10%

    NMT 5%

     

    NMT 2.5%

    Sulphates

    NMT 500ppm

    Barium

    Should comply

    Loss on drying

    6%~10%

    Sulphated ash

    NMT 0.1%

    Assay

    99.0 %-101.0 % on dried substance

    Application of Quinine HCL
    1. Quinine Hydrochloride is used as an antimalarial drug, and it is an active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.

    2. Quinine Hydrochloride is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.

    3. Quinine Hydrochloride used commonly as a bitter and flavoring agent, and it is still useful for the treatment of babesiosis. emeraldgo(at)hotmail.com.

    4. Quinine Hydrochloride is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.

    Function

     

    1.Quinine HCL powder is a substance that was first obtained by processing the bark of the cinchona tree, a South American native plant that has been used as a fever reducer by Native Americans for centuries. This substance has been used historically to treat malaria, along with some other medical conditions, and although a number of antimalarial drugs are on the market today, it is still used in some regions. It is also used commercially as an additive to tonic water, a soft drink that is used as a mixer for other drinks in addition to being consumed straight.

    2.Quinine HCL Powder is a natural white crystalline alkaloid having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), anti-inflammatory properties and a bitter taste. It is a stereoisomer of quinidine which, unlike Nature Quinine, is an anti-arrhythmic. Sulphate Quinine contains two major fused-ring systems: the aromatic quinoline and the bicyclic quinuclidine.

    Packaging & Shipping

    2

     

     

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    Our Services

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    Company Information

    Qingdao Xigema Chemical Co., Ltd. Import And Export Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

    The aim of Xigema is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.

    Qingdao Xigema has become the "Top 500 Chinese manufacturing companies","Top 20 of global chemical sales".Qingdao Xigema has 21 subsidiaries and holding companies.

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    A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.


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