1-1000 Kilograms
$475.00
≥1001 Kilograms
$473.00
Rebamipide 90098-04-7
1.Competitive price
2.Fast Delivery Within 2 days
3.SGS , BV, GMP,ISO approve
4.Professional factory
Item | Specification |
Appearance | White crystalline powder,bitter taste |
Solubility | Soluble in N,N dimethylformamide;very slightly soluble or practically insoluble in methanol and ethanol; practically insoluble in water. |
Optical Rotation | No optical rotation in N,N’-dimethylformamide(1→20) |
Melting point | About 291℃(Decomposition) |
Identification | Conforms |
Loss on drying | ≤3.0% |
Sulphated ash | ≤0.10% |
Heavy metals | ≤10ppm |
Chlorides | ≤280ppm |
Related Substance | M-chloro isomer≤0.15% O-chloro isomer≤0.15% Debenzoylated isomer≤0.15% Other single impurity≤0.1% Total impurities≤0.4% |
Residual solvent | Acetone≤0.5% Ethanol≤0.5% Acetic acid≤0.5% Dichloromethane≤0.06% Methanol≤0.3% |
Assay | 99.0%~101.0%(Calculated on dry basis) |
Conclusion | Conform to the specification of JP16 |
Production name:Rebamipide
Cas no.:90098-04-7
Purity: 99% min
MF:C19H15ClN2O4
Rebamipide | CAS 90098-04-7 | Brand: HB OCEAN |
MW: 370.072 | MSDS: Avaiable | |
MF : C19H15ClN2O4 | Sample: Avaiable | |
Category:Gastrointestinal Agents ; | Min order: 10grams | |
Quality standard : USP32/BP2007/EP7 | Place of Origin:China | |
Introduction | Rebamipide, an amino acid derivative of 2(1H)-quinolinone, is used for mucosal protection, healing of gastroduodenal ulcers, and treatment of gastritis. It works by enhancing mucosal defense, scavenging free radicals, and temporarily activating genes encoding cyclooxygenase-2. | |
Character | White crystalline power | |
Applications | Pharmaceutical raw materials |
R the pat chemical structure contains benzyl matchup of amide groups and the two have a carbonyl group 3, 4 a double bond, can a dose-dependent inhibition of neutrophil activation to produce reactive oxygen species, and can effectively remove free radicals, to prevent free radicals damage of gastric mucosa. This product can also promote gastric mucosa synthesis of prostaglandins and enhance gastric mucosal barrier. In addition, the product by preventing helicobacter pylori (Hp) lands on gastric epithelial cells, reducing oxidative stress, reduce the helicobacter pylori cytokine concentrations of Hp and inhibiting effect on gastric mucosa lesion.
Animal experiments show that ribapat can remove free radicals in mucosal epithelial cells and have significant inhibitory effects on the production of neutrophilic granulocytes. OH also has a scavenging effect, which can inhibit the generation of Hp and chemokines. By inhibiting the damage of bile acid to gastric mucosa, the synthesis of prostaglandins is increased.
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Company Information
QingdaoxigemaCHEMICAL Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of xigema is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
xigema has become the "Top 500 Chinese manufacturing companies","Top 20 of global agrochemical sales". xigema has 21 subsidiaries and holding companies.
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