API raw material Ranitidine Hydrochloride powder ranitidine hcl
  • Item No.TOP
    MOQ1 Kilogram / Kilograms
    description

     

     

    Basic Information

    Ranitidine, sold under the trade name Zantac among others, is a medication that decreases stomach acid production. It is commonly used in treatment of peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome.There is also tentative evidence of benefit for hives.It can be taken by mouth, by injection into a muscle, or into a vein

     

    Common side effects include headaches and pain or burning if given by injection. Serious side effects may include liver problems, a slow heart rate, pneumonia, and the potential of masking stomach cancer. It is also linked to an increased risk of Clostridium difficile colitis.It is generally safe in pregnancy. Ranitidine is an H2 histamine receptor antagonist that works by blocking histamine and thus decreasing the amount of acid released by cells of the stomach.

     

    Ranitidine was discovered in 1976 and came into commercial use in 1981. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.It is available as a generic medication. The wholesale price in the developing world is about 0.01 to 0.05 USD per pill. In the United States it is about 0.05 USD per dose.

    Basic Information

    Test Report

    Item

    Specification

    Result

    Appearance

    White crystalline powder

    Complies

    Related substance (HPLC)

    Total impurity ≤0.5%

    Max single impurity ≤0.1%

    0.2%

    0.06%

    Odor

    Characteristic

    Complies

    Assay

    99%

    99.8%

    Sieve analysis

    100% pass 80 mesh

    Complies

    Loss on Drying

    Residue on Ignition

    ≤1.0%

    ≤1.0%

    0.12%

    0.09%

    Heavy Metal

    <10ppm

    Complies

    As

    <0.1ppm

    0.05ppm

    Pb

    <0.1ppm

    0.05ppm

    Cd

    <0.1ppm

    0.05ppm

    Residual Solvents

    <100ppm

    Complies

    Residual Pesticide

    Negative

    Complies

    Microbiology

     

     

    Total Plate Count

    <1000cfu/g

    Complies

    Yeast & Mold

    <100cfu/g

    Complies

    E.Coli

    Negative

    Complies

    Salmonella

    Negative

    Complies

    Functions
     

    Application AreaUse of ranitidine in the treatment of recurrent aphthous ulcer, pain within 1-2 days 3-5 days to heal, the total effective rate of 100%, and metronidazole in the treatment of control group is 85%, there are significant differences. Usage: oral ranitidine 150 mg per time, 2 times per day, or ranitidine Ding Yan into fine powder and apply directly on the ulcer surface, 3 times per day until the symptoms disappear.


    Application of ranitidine in treatment of patients with mumps, the effect is significant, significantly better than the control group treated with Morpholine croak. Usage: oral ranitidine, 15 mg/kg ·, 2 suits, for 3 days in a row. If the heat is too high, and with physical cooling.


    Ranitidine was used to treat patients with ulcerative colitis, the total effective rate of 95%. Usage: oral ranitidine 150 mg per time, daily morning and evening 1, taken in March.
    Application of ranitidine in the treatment of Verrucous gastritis and achieve significant efficacy in one week, the total effective rate of 87%, while the control group only 33%, very significant differences between the two groups. Usage: oral ranitidine 150 mg per time, morning and evening, 1 times, warm water delivery service, for 1 course of 5 weeks.


    Application of ranitidine in treatment patients with Eosinophilic Fasciitis, with good results. General Medicine 1 month can be effective six months after the partial recovery of skin lesions. Usage: oral ranitidine 150 mg per time, early, middle and late each take 1 times, warm water delivery service.


    The disease may lead to increased intestinal mast cells, have been stimulated to release histamine, causing local congestion, edema, muscle cramps and diarrhea occurs. Ranitidine works by inhibiting histamine release and to good effect. Most patients stool within 1 week, less often, and get the healing effect. Usage: oral ranitidine 150 mg per time, early, middle, late 1 times, warm water delivery service.


    Use of ranitidine in the treatment of Herpes Simplex, typically coated with 3~5 pain away, early cases without a blister, blister blister dries up, scabs in 2 days. Ranitidine was also used in the treatment of 29 cases of herpes simplex are cured within 2-4 days. And no scar after healing occurs. Usage: take ranitidine capsules (150 mg), 1 capsule, the powder dissolved in water, made of exterior coating solution on the affected area, dressing 1 1-2 hours.


    Application of ranitidine in the treatment of urticaria, is satisfactory with medication after 1 treatment efficiency of 80%, the total effective rate of 90%. Methods: 5% ranitidine Ding Shuang agent, application of Yu Shenjue, wind pool, Xuehai, each point 50 mg, covers 3.5~6 square tape wound 1 time every 3 days, 2 times for 1 course, continuous treatment until symptoms disappear.

    Function

    1.For the treatment oe, a large number of ranitidine may inhibit gastric acid secretion, symptoms. Also used for general anesthesia or coma patients after major surgery and weakness to prevent acid reflux with inhalation pneumonia.
    2.Suitable for postoperative gastric ulcer, duodenal ulcer, ulcer, reflux esophagitis, etc.

    3.Clinical findings and ranitidine in the Treatment of Recurrent Aphthous ulcer and other diseases also have good effect.

     

    Packaging & Shipping

     

     

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    Company Information

    Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

    The aim of Qingdao Sigma Chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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    FAQ

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