1-1000 Kilograms
$100.00
≥1001 Kilograms
$10.00
Product Description
Nystatin is an antifungal medication. It is used to treat Candida infections of the skin including diaper rash, thrush, esophageal candidiasis, and vaginal yeast infections. It may also be used to prevent candidiasis in those who are at high risk. Nystatin may be used by mouth, in the vagina, or applied to the skin.
Like amphotericin B and natamycin, nystatin binds to ergosterol, a major component of the fungal cell membrane. When present in sufficient concentrations, it forms pores in the membrane that lead to K+ leakage and death of the fungus. Ergosterol is fairly unique to fungi, so the drug does not have such catastrophic effects on animals.
Certification of Analysis
Test items | Standard | Result | |
Description | Yellow brown powder | Conforms | |
Identification | IR | IR spectrum of sample is the same as working standard | Conforms |
HPLC | HPLC RT of the sample is the same as the working standard | Conforms | |
Melting point | 165.0°C~169.0°C | 165.8°C~167.0°C | |
Optical rotation | -23°~-29° | -27.4° | |
Loss on drying | NMT 1.0 % | 0.17% | |
Residue on ignition | NMT 0.1 % | 0.03% | |
Heavy metals | NMT 20ppm | Conforms | |
Related substances | |||
Impurity A | NMT 0.1 % | Not detected | |
Impurity B | NMT 0.1 % | Not detected | |
Impurity C | NMT 0.1 % | 0.02% | |
Single impurity | NMT 0.2 % | 0.17% | |
Total impurity | NMT 1.0 % | 0.60% | |
Assay | NLT 99.0% | 99.0% | |
Function
1. Nystatin is often used as prophylaxis in patients who are at risk for fungal infections.
2. It is prescribed in units, with doses varying from 100,000 (for oral infections) to 1 million (for intestinal ones). As it is not absorbed from the gut, it is safe for oral use and does not have problems of drug interactions.
3. It is also used in cellular biology as an inhibitor of the lipid raft-caveolae endocytosis pathway on mammalian cells, at concentrations around 3 µg/mL.
4. In certain cases, nystatin has been used to prevent the spread of mold on objects such as works of art.
Nystatin is also used as a tool by scientists performing "perforated" patch-clamp electrophysiologic recordings of cells. When loaded in the recording pipette, it allows for measurement of electrical currents without washing out the intracellular contents, because it forms pores in the cell membrane that are permeable to only monovalent ions.
Answer: Yes, we are factory founded on 2002.
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Q4:Can you give me a discount price?
Surely,It depend on your qty
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma Chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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