Factory provide high quality amphotericin b with best price 1397-89-3
  • Item No.amphotericin b
    MOQ100 Gram / Grams
    description
    Product Description

    Basic Information 

    Product Name: Amphotericin B

    Synonyms: mysteclin-f;ns718;nsc527017;Amphotericin B from Streptomyces sp;B AMPHOTERICIN B;AMPHOTERICIN;AMPHOTERICIN B SOLUTION;AMPHOTERICIN B CELL CULTURE TESTED

    CAS: 1397-89-3

    MF: C47H73NO17

    MW: 924.08

    EINECS: 215-742-2

     

    Amphotericin B  is a polyene antifungal drug, often used intravenously for systemic fungal infections. It was originally extracted from Streptomyces nodosus, a filamentousbacterium, in 1955 at the Squibb Institute for Medical Research from cultures of an undescribed streptomycete isolated from the soil collected in the Orinoco River region of Venezuela. Its name originates from the chemical's amphoteric properties. Two amphotericins, amphotericin A and amphotericin B are known, but only B is used clinically, because it is significantly more activein vivo. Amphotericin A is almost identical to amphotericin B (having a double C=C bond between the 27th and 28th carbons), but has little antifungal activity.
    Currently, the drug is available as plain amphotericin B, as a cholesteryl sulfate complex (ABCD), as a lipid complex (ABLC), and as a liposomal formulation (LAmB). The latter formulations have been developed to improve tolerability for the patient, but may show considerably different pharmacokinetic characteristics compared to plain amphotericin B.

    Functions

     

    Function

     Function of Amphotericin B

    1. One of the main intravenous uses is in treating various systemic fungal infections (e.g., in critically ill, comorbidly infected or immunocompromised patients), including cryptococcal meningitis.
    2. Amphotericin B is also commonly used in tissue culture to prevent fungi from contaminating cell cultures. It is usually sold in a concentrated solution, either on its own or in combination with the antibiotics penicillin and streptomycin.Antiprotozoan.
    3. Another IV use is as a drug of last resort in otherwise-untreatable parasitic protozoan infections such as visceral leishmaniasis and primary amoebic meningoencephalitis. 

    Application of Amphotericin B

    Amphotericin B is a pharmaceutical ingredient used for as an antifungal drug often used intravenously for systemic fungal infections.
    Amphotericin B is the only effective treatment for some fungal infections.

     

    Analysis

     

     

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    Packaging & Shipping

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    Company Information

    Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

    The aim of Qingdao Sigma Chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced
    processing technology and it has gained a high and reliable reputation from customers at both quality and services.

     

    Qingdao Sigma Chemical Co., Ltd has become the "Top 500 Chinese manufacturing companies",

    "Top 20 of global chemical sales".Qingdao Sigma Chemical Co., Ltdhas 21 subsidiaries and holding companies.

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    A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

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