[English Name]Spironolactone
[Test Method]HPLC
[Purity]≥99%
[CAS No.] 52-01-7
[Mol. Formula]C24H32O4S
[Purity]> 99% by HPLC
[Packaging] 25kgs/drum ...
Package and quantity according to customer's detail requirement
[Remark] In stock, customized for large scale.
Synthetic steroids, a low-potency diuretic, similar in structure to aldosterone, are competitive inhibitors of aldosterone. Since
the drug only acts on distal tubules and collecting tubes, it has no effect on other segments of the renal tubules, so the
diuretic effect is weak. In addition, the drug also has effects on aldosterone target organs other than the renal tubules.
Free Shipping API raw material 99% Spironolactone / CAS 52-01-7 / spironolactone powder
10-49 Grams
$2.00
50-99 Grams
$1.20
100-999 Grams
$1.00
≥1000 Grams
$0.43
description
Products Description
It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called
potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia,and Conn’s syndrome.
potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia,and Conn’s syndrome.
Specification
TEMS | SPECIFICATION | RESULTS |
APPEARANCE | WHITE OR ALMOST WHITE | ALMOST WHITE MINOR |
MINOR CRYSTALLINE POWDER | CRYSTALLINE POWDER | |
IDENTIFICATION | MEET THE REQUIREMENTS | MEET THE REQUIREMENTS |
MELTING RANGE | 198°C~209°C | 206.0°C~207.5°C |
SPECIFIC ROTATION | -33°~ -37° | -36° |
LOSS ON DRYING | ≤0.5% | 0.17% |
LIMIT OF MERCAPTO | ≤0.5% | 0.10% |
ORDINARY IMPURITIES | ≤0.2% | MEET THE REQUIREMENTS |
ORGANIC VOLATILE | MEET THE REQUIREMENTS | MEET THE REQUIREMENTS |
IMPURITIES | ||
METHANOL | ≤3000PPM | 14PPM |
TETRAHYDROFURAN | ≤720PPM | N.D. |
ASSAY(ON THE DRIED BASIS) | 97.0%~103.0%(HPLC) | 99.30% |
Function &Application
1.Edema disease is combined with other diuretics to treat edematous diseases such as congestive edema, cirrhosis of ascites, andrenal edema. The purpose is to correct the secondary aldosterone secretion associated with the disease and to counteract other
diuretics. Potassium effect. Also used for the treatment of idiopathic edema.
2.The role of hypertension is an adjuvant drug for the treatment of hypertension.
3.Primary aldosteronism can be used for the diagnosis and treatment of this disease.
4.The prevention of hypokalemia combined with thiazide diuretics enhances the diuretic effect and prevents hypokalemia.
Clinically used for the treatment of refractory edema associated with elevated aldosterone, it is more effective for patients with cirrhosis and nephrotic syndrome, but the effect of congestive heart failure except in patients with secondary aldosterone increased due to lack of sodium Both are poor.
diuretics. Potassium effect. Also used for the treatment of idiopathic edema.
2.The role of hypertension is an adjuvant drug for the treatment of hypertension.
3.Primary aldosteronism can be used for the diagnosis and treatment of this disease.
4.The prevention of hypokalemia combined with thiazide diuretics enhances the diuretic effect and prevents hypokalemia.
Clinically used for the treatment of refractory edema associated with elevated aldosterone, it is more effective for patients with cirrhosis and nephrotic syndrome, but the effect of congestive heart failure except in patients with secondary aldosterone increased due to lack of sodium Both are poor.
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Packaging & Shipping
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Company Information
Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma Chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
FAQ
Q1: Are you a manufacturer?
Answer: Yes, we are factory founded on 2002.
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Q4:Can you give me a discount price?
Surely,It depend on your qty
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
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