1-1000 Kilograms
$500.00
≥1001 Kilograms
$20.00
English name: dyphylline
English alias: Diprophylline; 7-(2,3-Dihydroxypropyl)theophylline, Dyphylline; Dilor; Teofen; Neufil;
CAS No.: 479-18-5
Molecular formula: C10H14N4O4
Molecular weight: 254.24300
Exact quality: 254.10200
Appearance and traits: white powder
Density: 1.57g/cm3
Melting point: 161-162 ° C (lit.)
Boiling point: 589.6oC at 760 mmHg
Flash point: 310.4oC
Refractive index: 1.5403 (172oC)
Water solubility: 33 g / 100 mL (25 oC)
Item | Specification |
Specific rotation | +39.5 to +41.5° |
State of solution(transmittance) | Clear 98.0% min. |
Chloride[cl] | 0.020% max. |
Ammonium [NH4] | 0.02% max. |
Sulfate[SO4] | 0.020% max |
Iron[Fe] | 10ppm max. |
Heavy metals [Pb] | 10ppm max |
Arsenic[As2O3] | 1ppm max |
Other amino acids | Chromatographically not detectable |
Loss on drying | 0.20% max. |
Residue on ignition[sulfated] | 0.10% max. |
Assay | 99.0% min |
Function
Dyphylline theophylline smooth muscle relaxant, has the effect of dilating bronchial and coronary arteries, and has a diuretic effect. Stable in gastric juice. The antiasthmatic effect is similar to aminophylline, especially for tachycardia. Applicable to bronchial asthma, wheezing bronchitis and other symptoms of wheezing.
Application
Dyphylline is an inhibitor to phosphodiesterase. It is used in the therapy of bronchial asthma, gasping bronchitis and gasping from cardiogenic pulmonary edema. It can soothe the symptom of gasping through loosening bronchial smooth muscle, increasing cardiac blood output, expanding kidney arteriole, increasing glomerulus filtration and renal blood flow, inhibiting distal end renal tubule's reabsorption of sodion and chloridion, and increasing contractility of hanging skeletal muscle. Its action of expanding bronchus is only one tenth of that of aminophylline. It can easily be absorbed orally, metabolize to derivants of theophylline in vivo, and are excreted with urine.
Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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