1-1000 Kilograms
$30.00
≥1001 Kilograms
$1.00
Chemical Name: Chlortetracycline hydrochloride Molecular Formula:C22H24Cl2N2O8 Molecular weight: 515.34 Appearance: Yellow powder |
As a broad-spectrum antibiotic, it has antibacterial effect on gram-positive and negative bacteria
Broad-spectrum antibiotics have antibacterial effect on gram-positive and negative bacteria.
The cell permeation fluorescence probe was used to measure the flow of the endoplasmic reticulum Ca2+.
Item | Specifications | Results |
Appearance | Yellow powder | Conforms |
Identification | ||
A | Thin-layer chromatography | Positive |
B | The colour becomes brownish | Positive |
C | It gives reaction(a)of chlorides | Positive |
D | Liquid chromatography | Positive |
PH | 2.3-3.3 | 2.64 |
Specific optical rotation | -250°~-235° | -241° |
Absorbance | ≤0.40,460nm | 0.229 |
Related substances | ||
Impurity A(4-eqichlortetracycline) | ≤4.0% | 1.18% |
Impurities B(demeclocycline) | ≤1.0% | 0.20% |
Impurities E(4-epidemethylchlortetracycline) | ≤1.0% | 0.48% |
Impurity J(anhydrotetracycline) | ≤0.3% | 0.05% |
Impurities D(4-epitetracycline) | ≤0.2% | 0.05% |
Impurities G(isochlortetracycline) | ≤0.2% | Not detected |
Impurities H(2-acetyl-2-decarboxamidochlorletracycline) | ≤0.2% | 0.06% |
Impurities L(anhydrochlortetracycline) | ≤0.2% | 0.09% |
Impurities K(4-epianhydrochlortetracycline) | ≤0.15% | Not detected |
Unspecified impurities | ||
Impurities C(4-epidemethyltetracycline) | ≤0.10% | Not detected |
Impurities F(4-eplisochlortetracycline) | ≤0.10% | Not detected |
Impurities I(4-epianhydrotetracycline) | ≤0.10% | Not detected |
Disregard limit | ≤0.05% | Conforms |
Sum of impurities other than A | ≤2.0% | 0.93% |
Heavy metals | ≤50ppm | <50ppm |
Water | ≤2.0% | 0.58% |
Sulfated ash | ≤0.5% | 0.12% |
Assay | ||
Chlortetracycline hydrochloride | ≥89.5% | 91.51% |
Tetracycline hydrochloride | ≤6.0% | 4.71% |
CTC.HCl+TC.HCl | 94.5~102.0% | 96.22% |
Ethanol | ≤0.5% | 0.40% |
Conclusion | The results conforms with EP8.0 standards | |
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