Nifuratel is nitrofuran derivatives, is a broad-spectrum antibiotics, it has broad-spectrum antimicrobial effect, the fungicidin is of alkenes antifungal drugs, To trichomonad, bacteria, candida albicans have strong activity, especially for gynecology infection pathogens such as gram-positive bacterium and Gram-negative bacterium, trichomonad, mould, chlamydia and mycoplasma have strong exterminate action. After absorbing the oral gastrointestinal tract, most of the renal excretion through in the blood and urine, genital organization have high concentration, therefore, in urinary system can produce strong antibacterial action, and its metabolites still has antibacterial activity, and eject as urine.

Test Items

Specification

Test results

Characters

Yellow crystalline powder

Yellow crystalline powder

Identification

Melting point

186.0-189.0 ℃

187.0-188.0 ℃

IR

Infrared absorption spectrophotometry accord with the nifuratel CRS.

Meet the specification

Chemical reaction

Positive reaction

Meet the specification

UV

The most absorption at 260nm and 365nm

Meet the specification

Colour of solution

NMT No.5 solution standard

Meet the specification

PH

5.5-7.0

6.54

Related substances

Any impurity ≤0.2%

0.03%

Total impurity ≤1.0%

0.07%

Loss on drying

≤0.5%

0.06%

Sulphated ash

≤0.1%

0.02%

Assay

98.5%~101.5%

100.4%

Residual Solvents

DMF ≤880ppm

Not detected

Methanol≤3000ppm

Not detected

Dichloromethane≤600ppm

Not detected