Top quality Rosuvastatin calcium with best price 147098-20-2
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    MOQ1 Kilogram / Kilograms
    description
    Product Description

        Product Description

     
                                
    NameRosuvastatin calcium
    Synonyms7-{4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
    Molecular Formula2(C22H27FN3O6S).Ca;C44H54CaF2N6O12S2
    Molecular Weight1001.14
    CAS Registry Number147098-20-2
    Melting point122 ºC

    Rosuvastatin Calcium is the calcium salt form of rosuvastatin, a statin with antilipidemic activity. Rosuvastatin selectively and competitively binds to and inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a precursor of cholesterol. This leads to a decrease in hepatic cholesterol levels and increase in uptake of LDL cholesterol.  

    Certification of Analysis

     

    Tests

    Specifications

    Results

    Appearance

    A White to off-white powder

    Complies

    Specific Rotation

    +17°~+21°

    +20°

    Identification

    A. Meets the requirement

    B. UV: λmax=243nm

    C. IR: similar to Reference Substance

    D.X-ray: similar to Reference Substance

    Complies

    Complies

    Complies

    Complies

    Chloride

    ≤0.1%

    Complies

    Sulphate

    ≤0.1%

    Complies

    Enantiomer

    ≤0.15%

    Undetected

    Calcium

    3.9%~4.3%

    4.1%

    Related substances

    Diastereomer≤0.15%

    0.06%

    5-oxo-Rosucastatin≤0.15%

    Undetected

    Photo degradation 1≤0.15%

    Undetected

    Photo degradation 2≤0.15%

    Undetected

    Rosuvastatin lactone≤0.15%

    Undetected

    Rosuvastatin methyl ester≤0.15%

    Undetected

    Rosuvastatin isoamyl ester≤0.15%

    Undetected

    Any unknown impurity≤0.10%

    0.05%

    Total impurities≤0.75%

    0.28%

    Water

    ≤3.0%

    2.1%

    Isoamyl Bromide

    ≤37.5ppm

    ≤37.5ppm

    Residual solvents

    Ethyl ether≤300ppm Undetected

    Complies

    Acetonitrile≤410ppm Undetected

    Undetected

    Isoamyl alcohol≤5000ppm Undetected

    Undetected

    DMF≤880ppm Undetected

    Undetected

    Assay

    98.5%~102.0%( caculated on the anhydrous basis)

    99.8%

     

     

                              Function&Application

     

     Rosuvastatin calcium is a HYDROXYMETHYLGLUTARYL-COA-REDUCTASE INHIBITOR, or statin, that reduces the plasma concentrations of LDL-CHOLESTEROL; APOLIPOPROTEIN B, and TRIGLYCERIDES while increasing HDL-CHOLESTEROL levels in patients with HYPERCHOLESTEROLEMIA and those at risk for CARDIOVASCULAR DISEASES.

     

     
    Packaging & Shipping

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    Our Services

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    FAQ
    Q1: Are you a manufacturer?
    Answer: Yes, we are factory founded on 2002.
     
    Q2: How to contact with us?
    Click the Alibaba "Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
     
    Q3:Which kind of payment terms do you accept?
    For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
     
    Q4:Can you give me a discount price?
    Surely,It depend on your qty
     
    Q5:How can i get a sample?
    free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
     
    Q6: How to confirm the Product Quality before placing orders?
    A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
     
    Q7:How do you treat quality complaint?
    A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
     
    Company Information

    Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
     
    The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.

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    REPUTION.jpg 
    our team

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