≥1 Kilograms
$916.66
Product Description
Product name:Emtricitabine/Emtricitabine powder
CAS No.: 143491-57-0
Einecs No:N/A
Appearance:white powder
Molecular Weight:247.25
Density:1.829g/cm3
Boiling Point:443.281°C at 760 mmHg
Melting Point:136-140°C
Flash Point:221.889°C
Storage Temperature:Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Solubility:Freely soluble in Methanol and Water; Practically insoluble in Dichloromethane
Usage:Animal Pharmaceuticals
Synonyms:SM-Q; 4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-(2r-cis)-2(1h)-pyrimidinone; (-)-BETA-2',3'-DIDEOXY-5-FLUORO-3'-THIACYTIDINE; EMTRITABINE; FUMITREMORGIN C; EMTRICITABIN; 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
Emtricitabine (FTC) is a nucleoside reverse transcriptase inhibitor (NRTI) for the treatment of HIV infection in adults and children.
Certification of Analysis
Item | Requirements | Test Results |
Description | A white or almost white crystalline powder | white crystalline powder |
Solubility | Freely soluble in Methanol and Water; Practically insoluble in Dichloromethane | Complies |
Identification | The infrared absorption spectrum is concordant with the spectrum obtained from Emtricitabine RS or with the reference spectrum of Emtricitabine | Complies |
| Determine the Specific Optical Rotation using a 2.5 mg/ml solution in water R and calculate with reference to the dried substance; [α]D20 °C = -105.0° to -115.0°. | -107.5° |
Limit of Emtricitabine Enantiomer | ≤0.30% | Not detected |
Loss on Drying | ≤0.5% (3 hours at 105°C) | 0.14% |
Residue on Ignition | ≤0.1% | Complies |
Related Substance | Any impurity before the principal Peak ≤0.5% | Complies |
| Not more than 2 impurities over 0.1% before the principal peak | Complies |
| Any impurity after the principal peak ≤0.7% | Complies |
| Not more than 2 impurities over 0.1% after the principal peak | Complies |
| Total impurities ≤1.0% | 0.10% |
Function&Application
This product is a new nucleoside reverse transcriptase inhibitor, HIV-.1, HIV-2 and HBV have antiviral activity. After oral administration of phosphorylated 5 '- three phosphate, 5' - three phosphate, 5 '- three phosphate by entering the main chain of the virus, binding to the main chain, leading to chain termination, thus inhibiting the activity of HIV-1 reverse transcriptase and HBV DNA polymerase. In clinic, it is combined with other antiretroviral drugs for the treatment of adult HIV-1 (AIDS) and the treatment of hepatitis B.
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