1-1000 Kilograms
$900.00
≥1001 Kilograms
$850.00
Product Description
Product Name: | Epalrestat |
Synonyms: | 3-thiazolidineaceticacid,5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo;5-((1z,2e)-2-methyl-3-phenylpropenylidene)-4-oxo-2-thioxo-3-thiazolidineacet;e)-(e;EPALRESTAT;(e,e)-2-[5-(2-methyl-3-phenyl-prop-2-enylidene)-4-oxo-2-sulfanylidene-thiazo lidin-3-yl]acetic acid;AKOS BBS-00007767;OTAVA-BB BB7211260020;EPALRESTAT(KINEDAK) |
CAS: | 82159-09-9 |
MF: | C15H13NO3S2 |
MW: | 319.4 |
Product Categories: | Treatment of diabetic neuropathy;API's;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds |
Mol File: | 82159-09-9.mol |
mp | 210-217 C |
storage temp. | -20°C Freezer |
Certification of Analysis
| Test Item | Test Specification |
Description | Orange to orange red crystalline power |
Solubility | Hardly soluble in water, slightly soluble in methanol, ethanol, acetone,easily soluble in tetrahydrofuran |
Indentification | Must meet |
LOD(105℃ for 3hrs) | NMT0.5% |
Residue on Ignition | NMT0.1% |
RelatedSubstances(By HPLC) | Individual impurity: NMT 0.5% Total impurities: NMT 1.0% |
Assay(By HPLC) | 98.0-102.0% ON DB |
Melting Point | 222-227℃ |
Heavy Metals | NMT 20ppm |
Function&Application
Epalrestat is an aldose reductase inhibitor. Long-term treatment with epalrestat is well tolerated and can effectively delay the progression of diabetic neuropathy and ameliorate the associated symptoms of the disease, particularly in subjects with good glycemic control and limited microangiopathy.
1. Epalresta is an aldose reductase inhibitor that acts reversibly to inhibit aldose reductase that converts glucose to sorbitol. It is used for the improvement of symptoms, abnormal vibrational sensation, abnormal heartbeat caused by diabetic nerve ending disorders.
2. Epalrestat is used to prevent and treat diabetes.
Epalrestat is an aldose reductase inhibitor.
"Long-term treatment with epalrestat is well tolerated and can effectively delay the progression of diabetic neuropathy and ameliorate the associated symptoms of the disease, particularly in subjects with good glycemic control and limited microangiopathy."
Qingdao Sigma chemical Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
Answer: Yes, we are factory founded on 2002.
Q2: How to contact with us?
Click the Alibaba "Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
Q4:Can you give me a discount price?
Surely,It depend on your qty
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
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